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Auro Pharma signs sub-licensing pact with MPP to develop HIV drug Back
(16:38, 30 Mar 2023)
The Cabotegravir tablets & long acting injectables were originally developed by ViiV Healthcare.

The Medicines Patent Pool (MPP) is a United Nations-backed public health organisation working to increase access to, and facilitate the development of, life-saving medicines for low and middle-income countries.

For the generic version of Cabotegravir, Aurobindo said that it will utilize their vertically integrated capabilities to develop in-house API manufacturing which will enable stronger control on supply chain and cost efficiencies.

The tablet and injectable dosage forms of the product will be produced at the APL Healthcare Unit IV, Naidupet, India, and at the new Eugia Sterile facility, Vizag, India, respectively. The company said that it has adequate capacities to meet the global demand for the product across the licensed territory.

Cabotegravir long acting (LA) injectable suspension for HIV prevention is the first and only longer acting injectable PrEP option proven superior to daily oral FTC/TDF in reducing HIV acquisition. It is an integrase strand transfer inhibitor (INSTI), which inhibits HIV replication by preventing the viral DNA from integrating into the genetic material of human immune cells (T-cells). This step is essential in the HIV replication cycle and is also responsible for establishing chronic disease.

K. Nithyananda Reddy, vice chairman & managing director of Aurobindo said, “This is the first time a longer acting injectable product for prevention of human immunodeficiency virus (HIV) infection will be made available in the LMIC, through this license. This product will be a good addition to Aurobindo's ARV portfolio and will further strengthen our leadership in the generic HIV medicine space. We are looking forward to start supplying the product at the earliest and to help reducing the risk of HIV type 1 (HIV-1) infection in certain adults and adolescents weighing at least 35kg.”

Charles Gore, executive director of the Medicines Patent Pool said, “Broadening access to this innovative long-acting HIV prevention medicine could significantly contribute to ending HIV transmission by providing people with a choice in their HIV prevention options.”

Aurobindo Pharma develops, manufactures and distributes generic pharmaceuticals, branded specialty pharmaceuticals and active pharmaceutical ingredients.

The company's consolidated net profit declined 18.8% to Rs 491.26 crore despite of 6.7% rise in net sales to Rs 6,387.97 crore in Q3 FY23 over Q3 FY22.

The scrip declined 0.29% to end at Rs 509.80 on Wednesday, 29 March 2023.

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